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KMID : 0882420140870050619
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Korean Journal of Medicine
2014 Volume.87 No. 5 p.619 ~ p.624
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Polycythemia Vera Presenting with Generalized Chorea: A Case Report and Review of the Literature
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Kim Sun-Woong
Yu Hyung-Min
Lee Yoon-Jeong
Kim Hee-Jin
Hur Mi-Na
Lee Hong-Gi
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Abstract
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Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by erythrocytosis. Clinical symptoms can range in severity from headache and tinnitus to thrombohemorrhagic complications. Neurologic symptoms are common at the onset of polycythemia; however, chorea due to PV is a rare complication. We present the case of a 77-year-old female who was referred to our hospital because of choreic movement of the limbs, head and face. She was diagnosed with JAK2V617F mutation-positive PV. Her chorea was completely resolved by phlebotomy combined with hydroxyurea and aspirin.
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KEYWORD
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Polycythemia vera, Chorea disorders
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